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Human Stem Cell Derived Hepatocytes人iPS干細(xì)胞分化來(lái)的肝細(xì)胞
Cellartis enhanced hiPS-HEP v2 kits 提供了可持續(xù)供應(yīng)的、成熟的人誘導(dǎo)多能干細(xì)胞(hiPS)來(lái)源的肝臟細(xì)胞。
在超過(guò)14天的檢測(cè)窗口期,hiPS-HEP細(xì)胞擁有功能性的藥物代謝機(jī)制,使其成為體外藥物研發(fā)、藥物代謝、和相關(guān)毒性研究的理想選擇。具備成熟、穩(wěn)健的代謝特征,支持其作為代謝疾病模型。
方便使用的試劑盒包括*的培養(yǎng)基和組份,用于長(zhǎng)期檢測(cè)。與其他肝臟細(xì)胞模型相比,培養(yǎng)的Cellartis hiPS-HEP細(xì)胞存活時(shí)間更長(zhǎng),進(jìn)而擁有更長(zhǎng)的檢測(cè)窗口用于慢性-毒性實(shí)驗(yàn)和作為代謝疾病模型研究。
Cellartis 升級(jí)版的人iPS細(xì)胞來(lái)源肝臟細(xì)胞
貨號(hào) | 產(chǎn)品描述 | 品牌 | 規(guī)格 | 價(jià)格 |
Y10133 | Cellartis® Enhanced hiPS-HEP v2 (from ChiPSC12) Kit 人iPS細(xì)胞來(lái)源肝臟細(xì)胞 | Cellartis | 1 kit | ¥20,000 |
Y10134 | Cellartis® Enhanced hiPS-HEP v2 (from ChiPSC18) Kit 人iPS細(xì)胞來(lái)源肝臟細(xì)胞 | Cellartis | 1 kit | ¥20,000 |
Y10135 | Cellartis® Enhanced hiPS-HEP v2 (from ChiPSC22) Kit 人iPS細(xì)胞來(lái)源肝臟細(xì)胞 | Cellartis | 1 kit | ¥20,000 |
人iPS細(xì)胞分化肝臟細(xì)胞產(chǎn)品組成
包括肝細(xì)胞、肝細(xì)胞復(fù)蘇和鋪板試劑盒、肝細(xì)胞維持培養(yǎng)基三部分。
具體組份:
1 vial of ~1.2 × 107 cells 1.2 × 107細(xì)胞
Hepatocyte thawing medium 肝臟細(xì)胞復(fù)蘇培養(yǎng)基
Hepatocyte coating 肝臟細(xì)胞包被液
Hepatocyte plating medium 肝細(xì)胞鋪板培養(yǎng)液
Hepatocyte washing medium 肝細(xì)胞清洗液
Hepatocyte long-term maintenance medium 肝臟細(xì)胞長(zhǎng)期維持培養(yǎng)基
人iPS細(xì)胞來(lái)源肝臟細(xì)胞產(chǎn)品應(yīng)用
Toxicity testing, including chronic toxicity assays 毒理學(xué)研究,包括慢些病毒理學(xué)分析
Drug discovery and development 藥物開(kāi)發(fā)
Metabolic studies 代謝研究
Metabolic disease modeling 代謝疾病模型
人iPS細(xì)胞來(lái)源肝臟細(xì)胞產(chǎn)品特點(diǎn)
Complete kit for thawing, plating, and culturing the provided cells
Highly homogeneous population with consistent performance between batches and over time
Cells are functional and stable for a 14-day assay window
Cells show long-term, stable CYP450 activities
Cells express key hepatocyte proteins, including α1AT, Alb, CK18, HNF4α, and E-cadherin
Cells secrete physiologically relevant levels of albumin and urea
Cells demonstrate functional insulin and glucose regulation
Cells show phase I and II enzyme activities
Cells demonstrate LDL uptake
圖:Cellartis enhanced hiPS-HEP cells可以穩(wěn)定表達(dá)CYP450 活性超過(guò)21天。
Cellartis升級(jí)版的人iPS細(xì)胞來(lái)源肝臟細(xì)胞由華雅再生醫(yī)學(xué)旗艦公司:紅榮微再(上海)生物工程技術(shù)有限公司授權(quán)代理。紅榮微再以“傳遞科學(xué)價(jià)值,服務(wù)科學(xué)研究”為宗旨,主營(yíng)干細(xì)胞、精準(zhǔn)醫(yī)療、細(xì)胞治療、器官再生四大板塊的產(chǎn)品。: 152 1681 4001 :316 808 6348。